ANO3 rabbit pAb
Vendor: ELK Biotechnology
SKU: ES18338
Regular price
$148.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB
Cellular localization
Cell membrane ; Multi-pass membrane protein . Shows an intracellular localization. .
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
63982
Human swiss prot no
Q9BYT9
Immunogen
Synthesized peptide derived from human ANO3 AA range: 518-568
Isotype
IgG
Product weight
0.005kg
Reactivity
Human; Mouse
Recommended dilutions
WB 1：500-2000
Source
Rabbit
Storage
-20°C/1 year
Background
Background
The protein encoded by this gene belongs to the TMEM16 family of predicted membrane proteins, that are also known as anoctamins. While little is known about the function of this gene, mutations in this gene have been associated with some cases of autosomal dominant craniocervical dystonia. Cells from individuals with a mutation in this gene exhibited abnormalities in endoplasmic reticulum-dependent calcium signaling. Studies in rat show that the rat ortholog of this protein interacts with, and modulates the activity of a sodium-activated potassium channel. Deletion of this gene caused increased pain sensitivity in the rat model system. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2015],
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More Info
ANO3 rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
