Anti-Obinutuzumab Polyclonal Antibody
Regular price
$405.00 USD
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Regular price
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Available in stock (500)
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
ELISA
Clonality
Polyclonal
Form
Liquid
Host
Rabbit
Immunogen
Obinutuzumab
Isotype
IgG
Notes
Antibodysystem can customize this product per customer's request including product size, buffer components, etc. For research use only.
Purification
Purified by antigen affinity column.
Specificity
The product is specific for Obinutuzumab. This antibody serves as an excellent positive control for Obinutuzumab immunogenicity (ADA) assays.
Storage
The product can be stored for 2 - 3 weeks at 2 to 8°C or for up to 12 months at -20°C. Avoid repeated freezing and thawing cycles.
Storage buffer
0.01M PBS, pH 7.4.
Target name
Rabbit polyclonal to Gazyva.
Background
Background
Obinutuzumab is a humanized anti-CD20 monoclonal antibody, originated by GlycArt Biotechnology AG and developed by Roche as a cancer treatment. It was approved under the trade name Gazyva by the US FDA in 2013, and as Gazyvaro by the EMA in Europe, for the treatment of chronic lymphocytic leukemia in combination with chemotherapy in treatment-naive patients, and as a second line treatment for follicular lymphoma. Obinutuzumab is a fully humanized monoclonal antibody that binds to an epitope on CD20 that partially overlaps with the epitope recognized by rituximab. Obinutuzumab binds to CD20 on B cells and causes these cells to be destroyed by engaging the adaptive immune system, directly activating intracellular apoptosis pathways, and activating the complement system.
Product Citations
Product Citations
More Info
More Info
Anti-Obinutuzumab Polyclonal Antibody
Regular price
$405.00 USD
Sale price
Regular price
Unit price
/per
