Anti-Ramucirumab Polyclonal Antibody
Regular price
$405.00 USD
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Regular price
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Available in stock (500)
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Alternative names
Rabbit polyclonal to REGN-10987.
Applications
ELISA
Clonality
Polyclonal
Form
Liquid
Host
Rabbit
Immunogen
Ramucirumab
Isotype
IgG
Notes
Antibodysystem can customize this product per customer's request including product size, buffer components, etc. For research use only.
Purification
Antigen affinity purification.
Specificity
The product is specific for Ramucirumab. This antibody serves as an excellent positive control for Ramucirumab immunogenicity (ADA) assays.
Storage
The product can be stored for 2-3 weeks at 2-8°C or for up to 12 months at -20°C. Avoid repeated freezing and thawing cycles.
Storage buffer
0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.
Background
Background
Ramucirumab (LY3009806) is a human monoclonal antibody (IgG1) against vascular endothelial growth factor receptor 2 (VEGFR2), a type II trans-membrane tyrosine kinase receptor expressed on endothelial cells. By binding to VEGFR2, ramucirumab prevents binding of its ligands (VEGF-A, VEGF-C, and VEGF-D), thereby preventing VEGF-stimulated receptor phosphorylation and downstream ligand-induced proliferation, permeability, and migration of human endothelial cells.
Product Citations
Product Citations
More Info
More Info
Anti-Ramucirumab Polyclonal Antibody
Regular price
$405.00 USD
Sale price
Regular price
Unit price
/per
