Apcin

Vendor: Abmole

Type: Molecular

SKU: M6447

$201.25 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Apcin, a ligand of Cdc20, is a potent and competitive anaphase-promoting complex/cyclosome (APC/C(Cdc20)) E3 ligase activity inhibitor. Apcin competitively inhibits APC/C-dependent ubiquitylation by binding to Cdc20 and preventing substrate recognition. Apcin is a cdc20 inhibitor; inhibits Cdc20-substrate interaction.
Casnumber
300815-04-7
Formula
C13H14Cl3N7O4
Mw
438.65
Psmiles
CC1=NC=C([N]1CCOC(=O)NC(NC2=NC=CC=N2)C(Cl)(Cl)Cl)[N+]([O-])=O
Purity
>99.0%
Solubility
DMSO 90 mg/mL
Apcin

Apcin

$201.25 USD