Apostatin-1

Vendor: Abmole

Type: Molecular

SKU: M21568

$172.50 USD
Shipping calculated at checkout.

Documents

Coa

Available in stock (500)

  • Customs clearance fees may apply
  • Worldwide shipping available.
For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Apostatin-1 (Apt-1) is a new type of TRADD inhibitor. Apostatin 1 can bind to TRADD-N (KD=2.17 μM), and destroy the binding of Apostatin 1 to TRADD-C and TRAF2. Apostatin-1 regulates ubiquitination of RIPK1 and beclin 1. By activating autophagy in cells accumulated by mutated tau, α-synuclein or huntingtin, Apostatin 1 blocked apoptosis and restored homeostasis.
Casnumber
2559703-06-7
Formula
C19H27N3OS
Mw
345.51
Psmiles
CN1CCN=C1SC(C(=O)NC2CCCCCC2)C3=CC=CC=C3
Purity
>99.0%
Solubility
DMSO ≥ 40 mg/mL
Target synonyms
Apt-1
Apostatin-1

Apostatin-1

$172.50 USD