ARK-2 (phospho Tyr12) rabbit pAb

ARK-2 (phospho Tyr12) rabbit pAb

Vendor: ELK Biotechnology

SKU: ES7990

$148.00 USD
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Available in stock (100)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Applications
WB;IHC;IF;ELISA
Cellular localization
Nucleus . Chromosome . Chromosome, centromere . Chromosome, centromere, kinetochore . Cytoplasm, cytoskeleton, spindle . Midbody . Localizes on chromosome arms and inner centromeres from prophase through metaphase and then transferring to the spindle midzone and midbody from anaphase through cytokinesis (PubMed:20929775). Colocalized with gamma tubulin in the midbody (PubMed:17726514). Proper localization of the active, Thr-232-phosphorylated form during metaphase may be dependent upon interaction with SPDYC (PubMed:20605920). Colocalized with SIRT2 during cytokinesis with the midbody (PubMed:17726514). Localization (and probably targeting of the CPC) to the inner centromere occurs predominantly in regions with overlapping mitosis-specific histone phosphorylations H3pT3 and H2ApT12 (PubMed
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
9212
Human swiss prot no
Q96GD4
Immunogen
The antiserum was produced against synthesized peptide derived from human AurB around the phosphorylation site of Tyr12. AA range:1-50
Isotype
IgG
Observed band
39kD
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Recommended dilutions
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Source
Rabbit
Storage
-20°C/1 year
ARK-2 (phospho Tyr12) rabbit pAb

ARK-2 (phospho Tyr12) rabbit pAb

$148.00 USD