AS 1269574

Vendor: Abmole

Type: Molecular

SKU: M6466

$126.50 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
AS1269574 is a potent, orally active GPR119 agonist with an EC50 of 2.5 μM in HEK293 cells expressing human GPR119. AS1269574 activates the TRPA1 cation channel and stimulates glucagon-like peptide-1 (GLP-1) secretion. AS1269574 specifically induced pancreatic β cells to secrete glucose-dependent insulin only under high glucose conditions. AS1269574 has potential for type 2 diabetes research.
Casnumber
330981-72-1
Formula
C13H14BrN3O
Mw
308.17
Psmiles
CC1=CC(=NC(=N1)C2=CC=C(Br)C=C2)NCCO
Purity
>99%
Solubility
DMSO 30.82 mg/mL
AS 1269574

AS 1269574

$126.50 USD