AS1949490

Vendor: Abmole

Type: Molecular

SKU: M27934

$189.75 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
AS1949490 is a potent, orally active, selective SHIP2 phosphatase inhibitor with IC50 values of 0.34, 0.62, 13, >50, >50, and >50 µM for Mouse SHIP2, Human SHIP2, Human SHIP1, Human PTEN, Human synaptojanin, and Human myotubularin, respectively. AS1949490 increases the phosphorylation of Akt, glucose consumption and glucose uptake. AS1949490 activates intracellular insulin signalling pathways. AS1949490 can be used for research of diabetes.
Casnumber
1203680-76-5
Formula
C20H18ClNO2S
Mw
371.88
Psmiles
CC(NC(=O)C1=C(OCC2=CC=C(Cl)C=C2)C=CS1)C3=CC=CC=C3
Purity
≥99.0%
Solubility
DMSO 50 mg/mL (Need ultrasonic and warming)
AS1949490

AS1949490

$189.75 USD