AST 487

Vendor: Abmole

Type: Molecular

SKU: M10932

$172.50 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
AST 487 is a RET kinase inhibitor,IC50 880 nM, inhibits RET autophosphorylation, downstream effector activation, and also inhibits Flt-3,IC50 520 nM.
Casnumber
630124-46-8
Formula
C26H30F3N7O2
Mw
529.56
Psmiles
CCN1CCN(CC1)CC2=C(C=C(NC(=O)NC3=CC=C(OC4=NC=NC(=C4)NC)C=C3)C=C2)C(F)(F)F
Purity
>99.0%
Solubility
DMSO ≥ 60 mg/mL
Target synonyms
NVP-AST 487
AST 487

AST 487

$172.50 USD