Ataxin-1 rabbit pAb
Vendor: ELK Biotechnology
SKU: ES1718
Regular price
$148.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB;IHC;IF;ELISA
Cellular localization
Cytoplasm . Nucleus . Colocalizes with USP7 in the nucleus. .
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
6310
Human swiss prot no
P54253
Immunogen
The antiserum was produced against synthesized peptide derived from human Ataxin 1. AA range:742-791
Isotype
IgG
Observed band
87kD
Product weight
0.005kg
Reactivity
Human;Mouse
Recommended dilutions
Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.
Source
Rabbit
Storage
-20°C/1 year
Background
Background
ataxin 1(ATXN1) Homo sapiens The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord. Clinically, ADCA has been divided into three groups: ADCA types I-III. ADCAI is genetically heterogeneous, with five genetic loci, designated spinocerebellar ataxia (SCA) 1, 2, 3, 4 and 6, being assigned to five different chromosomes. ADCAII, which always presents with retinal degeneration (SCA7), and ADCAIII often referred to as the `pure' cerebellar syndrome (SCA5), are most likely homogeneous disorders. Several SCA genes have been cloned and shown to contain CAG repeats in their coding regions. ADCA is caused by the expansion of the CAG repeats, producing an elongated polyglutamine tract in the corresponding protein. The expanded repeats are variable in size and unstable, usually increasing in size when transmitted
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Product Citations
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More Info
More Info
Ataxin-1 rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
