Ataxin-2L rabbit pAb

Ataxin-2L rabbit pAb

Item number: ES4628
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$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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Ataxin-2L rabbit pAb

Ataxin-2L rabbit pAb

$148.00

Ataxin-2L rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Rat;Mouse;
Applications
WB;ELISA
Source
Rabbit
Recommended dilutions
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Immunogen
The antiserum was produced against synthesized peptide derived from human ATXN2L. AA range:571-620
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
113kD
Geneid human
11273
Human swiss prot no
Q8WWM7
Cellular localization
Membrane ; Peripheral membrane protein . Cytoplasm . Nucleus speckle . Cytoplasmic granule . Predominantly cytoplasmic but is also detected in nuclear speckles (PubMed:23209657). Component of cytoplasmic stress granules (PubMed:23209657). Inhibition of methylation alters nuclear localization (PubMed:25748791). Methylation does not seem to be required for localization to stress granules under stress conditions (PubMed:25748791). .
This gene encodes an ataxin type 2 related protein of unknown function. This protein is a member of the spinocerebellar ataxia (SCAs) family, which is associated with a complex group of neurodegenerative disorders. Several alternatively spliced transcripts encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

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