Atrasentan hydrochloride

Vendor: Abmole

Type: Molecular

SKU: M8766

$195.50 USD
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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Atrasentan hydrochloride (ABT-627 hydrochloride) is a potent, orally active, selective endothelin A (ETA) receptor antagonist that inhibits ETA activity and blocks endothelin-induced cellular proliferation with an IC50 value of 0.0551 nM. It can be used in studies related to prostate cancer as well as IgA nephropathy (IgAN). It can be used in prostate cancer and IgA nephropathy (IgAN) related studies.
Casnumber
195733-43-8
Formula
C29H38N2O6 · HCl
Mw
547.08
Psmiles
CCCCN(CCCC)C(=O)CN1CC(C(C1C2=CC=C(C=C2)OC)C(=O)O)C3=CC4=C(C=C3)OCO4.Cl
Purity
>98%
Solubility
DMSO: 2 mg/mL
Target synonyms
ABT-627 hydrochloride; Abbott 147627
Atrasentan hydrochloride

Atrasentan hydrochloride

$195.50 USD