Avadomide

Vendor: Abmole

Type: Molecular

SKU: M14326

$425.50 USD
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Documents

Coa

Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Avadomide (CC 122) is an orally effective cereblon modulator. avadomide modulates cereblon E3 ligase activity and induces apoptosis in diffuse large B-cell lymphoma (DLBCL) cells. Avadomide has antitumor and immunomodulatory activities. CC-122 is more potent in degrading IKZF1 and IKZF3 than lenalidomide and has broader and enhanced antiproliferative activity in ABC- and GCB-DLBCL cell lines.
Casnumber
1015474-32-4
Mw
286.29
Psmiles
CC1=NC2=CC=CC(=C2C(=O)N1C3CCC(=O)NC3=O)N
Purity
>99%
Solubility
DMSO 33.33 mg/mL
Target synonyms
CC 122
Avadomide

Avadomide

$425.50 USD