AZ12601011

Vendor: Abmole

Type: Molecular

SKU: M57237

$552.00 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
AZ12601011 is an orally active, selective TGFBR1 kinase inhibitor with an IC50 of 18 nM and a Kd of 2.9 nM. AZ12601011 inhibits phosphorylation of SMAD2 via selectively inhibiting ALK4, TGFBR1, and ALK7. AZ12601011 inhibits mammary tumor growth.
Casnumber
2748337-86-0
Formula
C19H15N5
Mw
313.36
Psmiles
C1CC2=C(C1)N=C(N=C2N3C=CC4=C3C=CN=C4)C5=CC=CC=N5
Purity
≥99.0%
Solubility
DMSO 5 mg/mL
AZ12601011

AZ12601011

$552.00 USD