AZ3976

Vendor: Abmole

Type: Molecular

SKU: M28380

$385.25 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
AZ3976 is a potent plasminogen activator inhibitor type 1 (PAI-1) inhibitor with an IC50 value of 26 μM in an enzymatic chromogenic assay. AZ3976 is active with an IC50 of 16 μM in a plasma clot lysis assay. AZ3976 does not bind to active PAI-1 but bound reversibly to latent PAI-1. AZ3976 inhibits PAI-1 by enhancing the latency transition of active PAI-1. AZ3976 displays profibrinolytic activities in a human plasma clot lysis assay.
Casnumber
1418747-15-5
Formula
C15H19N5O3
Mw
317.34
Psmiles
CC(C)(C)OC(=O)N1CC(C1)NC2=NC3=C(C=CC=N3)C(=O)N2
Purity
≥98.0%
Solubility
DMSO 100 mg/mL (ultrasonic)
AZ3976

AZ3976

$385.25 USD