AZ5104

Vendor: Abmole

Type: Molecular

SKU: M4977

$414.00 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
AZ5104, the demethylated metabolite of AZD-9291, is a potent EGFR inhibitor with IC50 of <1 nM, 6 nM, 1 nM, and 25 nM for EGFR (L858R/T790M), EGFR (L858R), EGFR (L861Q), and EGFR (wildtype), respectively.
Casnumber
1421373-98-9
Formula
C27H31N7O2
Mw
485.58
Psmiles
COC1=C(NC2=NC=CC(=N2)C3=C[NH]C4=C3C=CC=C4)C=C(NC(=O)C=C)C(=C1)N(C)CCN(C)C
Purity
>99.0%
Solubility
10 mM in DMSO
AZ5104

AZ5104

$414.00 USD