β-1,4-Gal-T2 rabbit pAb

Name: β-1,4-Gal-T2 rabbit pAb
Brand: ELK Biotechnology
Price: 148.0 USD
Availability: InStock

Vendor: ELK Biotechnology

SKU: ES7862

$148.00 USD

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Applications

IHC;IF;ELISA

Cellular localization

Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Trans cisternae of Golgi stack.

Clonality

Polyclonal

Concentration

1 mg/ml

Geneid human

8704

Human swiss prot no

O60909

Immunogen

Synthesized peptide derived from the C-terminal region of human β-1,4-Gal-T2.

Isotype

IgG

Product weight

0.005kg

Reactivity

Human;Mouse

Recommended dilutions

Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

Source

Rabbit

Storage

-20°C/1 year

Background

This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme encoded by this gene synthesizes N-acetyllactosamine in glycolipids and glycoproteins. Its substrate specificity i

β-1,4-Gal-T2 rabbit pAb

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