B23 (phospho Thr234) rabbit pAb

B23 (phospho Thr234) rabbit pAb

Vendor: ELK Biotechnology

SKU: ES6412

$148.00 USD
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Available in stock (100)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Applications
WB;IHC;IF;ELISA
Cellular localization
Nucleus, nucleolus . Nucleus, nucleoplasm . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Generally nucleolar, but is translocated to the nucleoplasm in case of serum starvation or treatment with anticancer drugs. Has been found in the cytoplasm in patients with primary acute myelogenous leukemia (AML), but not with secondary AML. Can shuttle between cytoplasm and nucleus. Co- localizes with the methylated form of RPS10 in the granular component (GC) region of the nucleolus. Colocalized with nucleolin and APEX1 in nucleoli. Isoform 1 of NEK2 is required for its localization to the centrosome during mitosis.
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
4869
Human swiss prot no
P06748
Immunogen
The antiserum was produced against synthesized peptide derived from human NPM around the phosphorylation site of Thr234. AA range:201-250
Isotype
IgG
Observed band
38kD
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Recommended dilutions
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Source
Rabbit
Storage
-20°C/1 year
B23 (phospho Thr234) rabbit pAb

B23 (phospho Thr234) rabbit pAb

$148.00 USD