B2LA1 rabbit pAb

B2LA1 rabbit pAb

Item number: ES11812
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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B2LA1 rabbit pAb

B2LA1 rabbit pAb

$148.00

B2LA1 rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Mouse
Applications
WB;ELISA
Source
Rabbit
Recommended dilutions
WB 1:500-2000 ELISA 1:5000-20000
Immunogen
Synthesized peptide derived from part region of human protein
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
19kD
Geneid human
597
Human swiss prot no
Q16548
Cellular localization
Cytoplasm .
BCL2 related protein A1(BCL2A1) Homo sapiens This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators that are involved in a wide variety of cellular activities such as embryonic development, homeostasis and tumorigenesis. The protein encoded by this gene is able to reduce the release of pro-apoptotic cytochrome c from mitochondria and block caspase activation. This gene is a direct transcription target of NF-kappa B in response to inflammatory mediators, and is up-regulated by different extracellular signals, such as granulocyte-macrophage colony-stimulating factor (GM-CSF), CD40, phorbol ester and inflammatory cytokine TNF and IL-1, which suggests a cytoprotective function that is essential for lymphocyte activation as well as cell survival. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [p

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