Baccatin III

Vendor: Abmole

Type: Molecular

SKU: M16492

$103.50 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Baccatin III is an orally available, selective inhibitor of the TGF-β1 signaling pathway and myeloid-derived suppressor cell (MDSC) activation. Baccatin III targets the AKT/STAT6 and Smad2/3 pathways, blocking TGF-β1-induced fibroblast differentiation and MDSC-mediated immunosuppression. Baccatin III exerts anti-inflammatory and anti-fibrotic effects by inhibiting macrophage activation and extracellular matrix deposition.
Casnumber
27548-93-2
Formula
C31H38O11
Mw
586.63
Psmiles
CC(=O)OC1C(=O)C2(C)C(O)CC3OCC3(OC(C)=O)C2C(OC(=O)C4=CC=CC=C4)C5(O)CC(O)C(=C1C5(C)C)C
Purity
>99.0%
Solubility
DMSO 29 mg/mL
Baccatin III

Baccatin III

$103.50 USD