BCATc Inhibitor 2

Vendor: Abmole

Type: Molecular

SKU: M21208

$287.50 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
BCATc Inhibitor 2 is a sulfonyl hydrazide that inhibits BCATc with IC50s of 0.81 for human and IC50 s of 0.2 µM for rat. It is 15-fold selectivity over BCATm. It has also been used to block calcium influx into neurons with IC50 of 4.8 µM following inhibition of glutamate uptake and to demonstrate neuroprotective efficacy in an in vivo rat model of neurodegeneration.
Casnumber
406191-34-2
Formula
C16H10ClF3N2O4S
Mw
418.7748096
Psmiles
C1=CC=C(C(=C1)C(F)(F)F)S(=O)(=O)NNC(=O)C2=CC3=C(O2)C=CC(=C3)Cl
Purity
>99%
Solubility
DMSO ≥ 200 mg/mL
BCATc Inhibitor 2

BCATc Inhibitor 2

$287.50 USD