Belnacasan

Vendor: Abmole

Type: Molecular

SKU: M3532

$101.20 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Belnacasan (VX-765) is a potent and selective inhibitor of caspase-1 with Ki of 0.8 nM. Belnacasan (VX-765) inhibits the release of LPS-induced IL-1β and IL-18 by human PBMCs with an IC50 of ~0.7 μM.
Casnumber
273404-37-8
Formula
C24H33ClN4O6
Mw
509.0
Psmiles
CCOC1OC(=O)CC1NC(=O)C2CCCN2C(=O)C(NC(=O)C3=CC(=C(N)C=C3)Cl)C(C)(C)C
Purity
99.68%
Solubility
DMSO 90 mg/mL
Target synonyms
VX-765
Belnacasan

Belnacasan

$101.20 USD