BI-0474

Vendor: Abmole

Type: Molecular

SKU: M21533

$1,466.25 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
BI-0474 is a covalent KRASG12C inhibitor. The IC50 value for GDP-KRAS::SOS1 protein-protein interaction was 7.0 nM. BI-0474 also showed better antitumor activity in non-small cell lung cancer xenograft models.
Casnumber
2750570-55-7
Formula
C30H37N9O2S
Mw
587.74
Psmiles
CC1CN(CCN1C2=CC(=CC(=N2)C3=NOC(=N3)C4(CCCC5=C4C(=C(S5)N)C#N)C)N6CCN(CC6)C(=O)C=C)C
Purity
＞99%
BI-0474

BI-0474

$1,466.25 USD