Birinapant

Vendor: Abmole

Type: Molecular

SKU: M2166

$161.00 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Birinapant (TL32711) is a bivalent Smac analogue, which is a potent antagonist of XIAP and cIAP1 with Kd values of 45 nM and less than 1 nM, respectively. Birinapant (TL32711) induces autoubiquitination and proteasome degradation of cIAP1 and cIAP2 in intact cells, resulting in the formation of RIPK1: Caspase-8 complex, which activates and induces tumor cell death.
Casnumber
1260251-31-7
Formula
C42H56F2N8O6
Mw
806.94
Psmiles
CCC(NC(=O)C(C)NC)C(=O)N1CC(O)CC1CC2=C([NH]C3=C2C=CC(=C3)F)C4=C(CC5CC(O)CN5C(=O)C(CC)NC(=O)C(C)NC)C6=C([NH]4)C=C(F)C=C6
Purity
99.63%
Solubility
DMSO 70 mg/mL
Target synonyms
TL32711
Birinapant

Birinapant

$161.00 USD