BMS-1166 hydrochloride

Vendor: Abmole

Type: Molecular

SKU: M29255

$414.00 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
BMS-1166 hydrochloride is a potent PD-1/PD-L1 immune checkpoint inhibitor. BMS-1166 hydrochloride induces dimerization of PD-L1 and blocks its interaction with PD-1, with an IC50 of 1.4 nM. BMS-1166 hydrochloride antagonizes the inhibitory effect of PD-1/PD-L1 immune checkpoint on T cell activation.
Casnumber
2113650-05-6
Formula
C36H34Cl2N2O7
Mw
677.57
Psmiles
CC1=C(C=CC=C1C2=CC3=C(C=C2)OCCO3)COC4=C(C=C(C(=C4)OCC5=CC(=CC=C5)C#N)CN6CC(CC6C(=O)O)O)Cl.Cl
Purity
≥99.0%
Solubility
DMSO ≥ 100 mg/mL
BMS-1166 hydrochloride

BMS-1166 hydrochloride

$414.00 USD