BMS-688521

Vendor: Abmole

Type: Molecular

SKU: M30828

$667.00 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
BMS-688521 is a highly potent, orally active inhibitor of the LFA-1/ICAM interaction, with an IC50 of 2.5 nM in the adhesion assay and an IC50 of 60 nM in the MLR assay. BMS-688521 is efficacious in a mouse allergic eosinophilic lung inflammation model.
Casnumber
893397-44-9
Formula
C26H19Cl2N5O4
Mw
536.37
Psmiles
CN1C(=O)N(C(=O)C12CN(CC2C3=CC=C(C=C3)C#N)C4=NC=C(C=C4)C(=O)O)C5=CC(=CC(=C5)Cl)Cl
Purity
≥99.0%
Solubility
DMSO 100 mg/mL (ultrasonic)
BMS-688521

BMS-688521

$667.00 USD