BMS CCR2 22

Vendor: Abmole

Type: Molecular

SKU: M30109

$437.00 USD
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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
BMS CCR2 22 is a potent, specific and high affinity CC-type chemokine receptor 2 (CCR2) antagonist with excellent binding affinity (binding IC50 of 5.1 nM) and potent functional antagonism (calcium flux IC50 of 18 nM and chemotaxis IC50 of 1 nM).
Casnumber
445479-97-0
Formula
C28H34F3N5O4S
Mw
593.66
Psmiles
CC(C)NC(=O)NC1=C(C=C(C=C1)C(F)(F)F)C(=O)NCC(=O)NC2CCCCC2NC(=O)C3=CC=C(C=C3)SCCC(C)NC(=O)NC1=C(C=C(C=C1)C(F)(F)F)C(=O)NCC(=O)NC2CCCCC2NC(=O)C3=CC=C(C=C3)SCCC(C)NC(=O)NC1=C(C=C(C=C1)C(F)(F)F)C(=O)NCC(=O)NC2CCCCC2NC(=O)C3=CC=C(C=C3)SC
Purity
≥99.0%
Solubility
DMSO 250 mg/mL (ultrasonic)
BMS CCR2 22

BMS CCR2 22

$437.00 USD