BMX-IN-1

Vendor: Abmole

Type: Molecular

SKU: M14880

$327.75 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
BMX-IN-1 is a selective, irreversible inhibitor of bone marrow tyrosine kinase on chromosome X (BMX) that targets Cys496 in the BMX ATP binding domain with an IC50 of 8 nM, also targets the related Bruton’s tyrosine kinase (BTK) with an IC50 value of 10.4 nM, but is more than 47-656-fold less potent against Blk, JAK3, EGFR, Itk, or Tec activity.
Casnumber
1431525-23-3
Mw
524.59
Psmiles
CC1=C(C=C(C=C1)N2C(=O)C=CC3=CN=C4C=CC(=CC4=C32)C5=CC=C(C=C5)NS(=O)(=O)C)NC(=O)C=C
Purity
>99%
Solubility
DMF 10 mg/mL; DMSO 8.33 mg/mL
Target synonyms
BMX kinase inhibitor
BMX-IN-1

BMX-IN-1

$327.75 USD