Bractoppin

Vendor: Abmole

Type: Molecular

SKU: M21649

$212.75 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Bractoppin is a potent and selective inhibitor of phosphopeptide recognition by the human BRCA1 tandem(t) BRCT domain with IC50 of 74 nM. Bractoppin diminishes BRCA1 recruitment to DNA breaks, in turn suppressing damage-induced G2 arrest and assembly of the recombinase, RAD51.
Casnumber
2290527-07-8
Formula
C25H23FN4O
Mw
414.47
Psmiles
FC1=CC=CC=C1CN2CCN(CC2)C(=O)C3=CC=C4N=C([NH]C4=C3)C5=CC=CC=C5
Purity
>99%
Solubility
DMSO ≥ 90 mg/mL
Bractoppin

Bractoppin

$212.75 USD