BRD3308

Vendor: Abmole

Type: Molecular

SKU: M8594

$178.25 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
BRD3308 is a highly selective HDAC3 inhibitor with an IC50 of 54 nM. BRD3308 is 23 times more selective to HDAC3 than HDAC1 (IC50:1.26 μM) or HDAC2 (IC50:1.34 μM). BRD3308 inhibits pancreatic β cell apoptosis induced by inflammatory cytokines or glucolipid toxic stress and increases functional insulin release. BRD3308 also activates HIV-1 transcription and disrupts HIV-1 latency.
Casnumber
1550053-02-5
Formula
C15H14FN3O2
Mw
287.29
Psmiles
CC(=O)NC1=CC=C(C=C1)C(=O)NC2=CC=C(F)C=C2N
Purity
>98.5%
Solubility
DMSO: 10 mg/mL
BRD3308

BRD3308

$178.25 USD