BRD6989

Vendor: Abmole

Type: Molecular

SKU: M20751

$132.25 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
BRD6989 is a selective inhibitor of CDK8 and CDK19. BRD6989 selectively binds a complex of CDK8 with an IC50 of ~200 nM. BRD6989 inhibits the kinase activity of recombinant CDK8 or CDK19 complexes. BRD6989 upregulates IL-10. BRD6989 is an analog of the natural product cortistatin A (dCA).
Casnumber
642008-81-9
Formula
C16H16N4
Mw
264.33
Psmiles
CC1CCC2=C(C1)C(=C(C#N)C(=N2)N)C3=CN=CC=C3
Purity
>99.0%
Solubility
DMSO 25 mg/mL
BRD6989

BRD6989

$132.25 USD