Bruceantinol

Vendor: Abmole

Type: Molecular

SKU: M19040

$575.00 USD
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Coa

Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Bruceantinol is a STAT3 inhibitor demonstrating potent antitumor activity in in vitro and in vivo human colorectal cancer (CRC) models. Bruceantinol strongly inhibits STAT3 DNA-binding ability (IC50=2.4 pM), blocks the constitutive and IL-6-induced STAT3 activation, and suppresses transcription of MCL-1, PTTG1, survivin and c-Myc.
Casnumber
53729-52-5
Formula
C30H38O13
Mw
606.61
Psmiles
CC(C)(/C(/C)=C/C(O[C@H]([C@H]1[C@]([C@H]([C@@H]2O)O)(C(OC)=O)OC[C@@]1([C@@H](C1)O3)[C@H]2[C@@](C)(CC2=O)[C@@H]1C(C)=C2O)C3=O)=O)OC(C)=O
Purity
>98.5%
Solubility
DMSO 50 mg/mL
Bruceantinol

Bruceantinol

$575.00 USD