BT2

Vendor: Abmole

Type: Molecular

SKU: M29950

$46.00 USD
Shipping calculated at checkout.

Documents

Coa

Available in stock (500)

  • Customs clearance fees may apply
  • Worldwide shipping available.
For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
BT2 is a BCKDC kinase (BDK) inhibitor with an IC50 of 3.19 μM. BT2 binding to BDK triggers helix movements in the N-terminal domain, resulting in the dissociation of BDK from the branched-chain α-ketoacid dehydrogenase complex (BCKDC). BT2 is also a potent and selective Mcl-1 inhibitor with a Ki value of 59 μM.
Casnumber
34576-94-8
Formula
C9H4Cl2O2S
Mw
247.1
Psmiles
OC(=O)C1=C(Cl)C2=CC=C(Cl)C=C2S1
Purity
>98.5%
Solubility
DMSO 60 mg/mL (ultrasonic)
BT2

BT2

$46.00 USD