BTRX-335140

Vendor: Abmole

Type: Molecular

SKU: M21654

$598.00 USD
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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
BTRX-335140 is a selective and orally active κ opioid receptor (KOR) antagonist, has antagonist activity for κOR, μOR and δOR with IC50 values of 0.8 nM, 110 nM, and 6500 nM, respectively. Navacaprant endows with favorable in vitro ADMET and in vivo pharmacokinetic profiles and medication-like duration of action in rats.
Casnumber
2244614-14-8
Formula
C25H32FN5O2
Mw
453.55
Psmiles
CCC1=CC2=C(C(=C(N=C2C(=C1)F)N3CCC(CC3)NC4CCOCC4)C5=NC(=NO5)C)C
Purity
>99%
Solubility
DMSO ≥ 10 mg/mL
Target synonyms
CYM-53093
BTRX-335140

BTRX-335140

$598.00 USD