c-di-AMP disodium

Vendor: Abmole

Type: Molecular

SKU: M58676

$253.00 USD
Shipping calculated at checkout.

Documents

Coa

Available in stock (500)

  • Customs clearance fees may apply
  • Worldwide shipping available.
For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
c-di-AMP disodium is a STING agonist, which binds to the transmembrane protein STING thereby activating the TBK3-IRF3 signaling pathway, subsequently triggering the production of type I IFN and TNF. c-di-AMP disodium is also a bacterial second messenger, which regulates cell growth, survival, and virulence, primarily within Gram-positive bacteria, and also regulates host immune response.
Casnumber
2734909-87-4
Formula
C20H22N10Na2O12P2
Mw
702.38
Psmiles
C1C2C(C(C(O2)N3C=NC4=C(N=CN=C43)N)O)OP(=O)(OCC5C(C(C(O5)N6C=NC7=C(N=CN=C76)N)O)OP(=O)(O1)[O-])[O-].[Na+].[Na+]
Purity
≥99.0%
Solubility
DMSO 120 mg/mL; Water 50 mg/mL
Target synonyms
Cyclic diadenylate disodium; Cyclic-di-AMP disodium
c-di-AMP disodium

c-di-AMP disodium

$253.00 USD