Cabozantinib malate

Vendor: Abmole

Type: Molecular

SKU: M4894

$138.00 USD
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Available in stock (500)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Cabozantinib malate (XL184) is the malate of Cabozantinib, a potent VEGFR2 inhibitor with IC50 of 0.035 nM and also inhibits c-Met, Ret, Kit, Flt-1/3/4, Tie2, and AXL with IC50 of 1.3 nM, 4 nM, 4.6 nM, 12 nM/11.3 nM/6 nM, 14.3 nM and 7 nM in cell-free assays, respectively.
Casnumber
1140909-48-3
Formula
C28H24FN3O5.C4H6O5
Mw
635.59
Psmiles
COC1=CC2=C(C=C1OC)C(=CC=N2)OC3=CC=C(NC(=O)C4(CC4)C(=O)NC5=CC=C(F)C=C5)C=C3.OC(CC(O)=O)C(O)=O
Purity
>99.0%
Solubility
DMSO 100 mg/mL; Water <1 mg/mL
Target synonyms
XL184;Cabozantinib S-malate
Cabozantinib malate

Cabozantinib malate

$138.00 USD