CAD12 rabbit pAb
Vendor: ELK Biotechnology
SKU: ES10503
Regular price
$148.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB;ELISA
Cellular localization
Cell membrane; Single-pass type I membrane protein.
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
1010
Human swiss prot no
P55289
Immunogen
Synthesized peptide derived from human protein . at AA range: 500-580
Isotype
IgG
Observed band
87kD
Product weight
0.005kg
Reactivity
Human;Mouse
Recommended dilutions
WB 1:500-2000 ELISA 1:5000-20000
Source
Rabbit
Storage
-20°C/1 year
Background
Background
This gene encodes a type II classical cadherin of the cadherin superfamily. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature cadherin protein. These integral membrane proteins mediate calcium-dependent cell-cell adhesion and are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a histidine-alanine-valine (HAV) cell adhesion recognition sequence specific to type I cadherins. This particular cadherin appears to be expressed specifically in the brain and its temporal pattern of expression would be consistent with a role during a critical period of neuronal development, perhaps specifically during synaptogenesis. [p
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More Info
More Info
CAD12 rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
