Cadherin-8 rabbit pAb

Cadherin-8 rabbit pAb

Item number: ES4419
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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Cadherin-8 rabbit pAb

Cadherin-8 rabbit pAb

$148.00

Cadherin-8 rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Applications
WB;IHC;IF;ELISA
Source
Rabbit
Recommended dilutions
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Immunogen
The antiserum was produced against synthesized peptide derived from human CDH8. AA range:491-540
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
90kD
Geneid human
1006
Human swiss prot no
P55286
Cellular localization
Cell membrane; Single-pass type I membrane protein.
This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. The extracellular domain consists of 5 subdomains, each containing a cadherin motif, and appears to determine the specificity of the protein's homophilic cell adhesion activity. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. This particular cadherin is expressed in brain and is putatively involved in synaptic adhesion, axon outgrowth and guidance. [provided by RefSeq, Jul 2008],

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