Calpain 10 rabbit pAb

Name: Calpain 10 rabbit pAb
Brand: ELK Biotechnology
Price: 148.0 USD
Availability: InStock

Vendor: ELK Biotechnology

SKU: ES4603

$148.00 USD

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Applications

WB;ELISA

Cellular localization

intracellular,cell,mitochondrion,cytosol,plasma membrane,

Clonality

Polyclonal

Concentration

1 mg/ml

Geneid human

11132

Human swiss prot no

Q9HC96

Immunogen

Synthesized peptide derived from the N-terminal region of human Calpain 10.

Isotype

IgG

Observed band

75kD

Product weight

0.005kg

Reactivity

Human;Rat;Mouse;

Recommended dilutions

Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.

Source

Rabbit

Storage

-20°C/1 year

Background

Calpains represent a ubiquitous, well-conserved family of calcium-dependent cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large catalytic subunit has four domains: domain I, the N-terminal regulatory domain that is processed upon calpain activation; domain II, the protease domain; domain III, a linker domain of unknown function; and domain IV, the calmodulin-like calcium-binding domain. This gene encodes a large subunit. It is an atypical calpain in that it lacks the calmodulin-like calcium-binding domain and instead has a divergent C-terminal domain. It is similar in organization to calpains 5 and 6. This gene is associated with type 2 or non-insulin-dependent diabetes mellitus (NIDDM), and is located within the NIDDM1 region. Multiple alternative transcript variants have been described for this gene. [provided by RefSeq,

Calpain 10 rabbit pAb

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