CaMK2 (Phospho-Thr286) Rabbit pAb

CaMK2 (Phospho-Thr286) Rabbit pAb

Item number: ES17871
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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CaMK2 (Phospho-Thr286) Rabbit pAb

CaMK2 (Phospho-Thr286) Rabbit pAb

$148.00

CaMK2 (Phospho-Thr286) Rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human; Mouse; Rat
Applications
WB; ELISA
Source
Rabbit
Recommended dilutions
WB 1:500-2000, ELISA(peptide)1:5000-20000
Immunogen
Synthesized pospho peptide derived from human CaMK2 (Phospho-Thr286)
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
54kD
Geneid human
817
Human swiss prot no
Q9UQM7/Q13557
Cellular localization
Cell junction, synapse . Cell junction, synapse, postsynaptic density . Cell projection, dendritic spine . Cell projection, dendrite . Postsynaptic lipid rafts. .
The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Nov 2008],

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