CaMKIIα/β/δ (phospho Thr305) rabbit pAb

CaMKIIα/β/δ (phospho Thr305) rabbit pAb

Item number: ES1415
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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CaMKIIα/β/δ (phospho Thr305) rabbit pAb

CaMKIIα/β/δ (phospho Thr305) rabbit pAb

$148.00

CaMKIIα/β/δ (phospho Thr305) rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Mouse;Rat
Applications
WB;IHC;IF;ELISA
Source
Rabbit
Recommended dilutions
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Immunogen
The antiserum was produced against synthesized peptide derived from human CaMK2 alpha/beta/delta around the phosphorylation site of Thr305. AA range:271-320
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
54kD
Geneid human
816/817
Human swiss prot no
Q9UQM7/Q13554/Q13557
Cellular localization
Cell junction, synapse . Cell junction, synapse, postsynaptic density . Cell projection, dendritic spine . Cell projection, dendrite . Postsynaptic lipid rafts. .
The product of this gene belongs to the serine/threonine protein kinases family, and to the Ca(2+)/calmodulin-dependent protein kinases subfamily. Calcium signaling is crucial for several aspects of plasticity at glutamatergic synapses. This calcium calmodulin-dependent protein kinase is composed of four different chains: alpha, beta, gamma, and delta. The alpha chain encoded by this gene is required for hippocampal long-term potentiation (LTP) and spatial learning. In addition to its calcium-calmodulin (CaM)-dependent activity, this protein can undergo autophosphorylation, resulting in CaM-independent activity. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Nov 2008],

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