Capivasertib (AZD5363)

Vendor: Abmole

Type: Molecular

SKU: M2303

$126.50 USD
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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Capivasertib (AZD5363) is a potentially first-in-class, orally effective pan-AKT inhibitor with strong inhibition against all three AKT isomers (AKT1/2/3) at an IC50 of 3 nM/8 nM/8 nM. It also showed similar inhibitory effect on P70S6K/PKA and low inhibitory activity on ROCK1/2.
Casnumber
1143532-39-1
Formula
C21H25ClN6O2
Mw
428.92
Psmiles
NC1(CCN(CC1)C2=NC=NC3=C2C=C[NH]3)C(=O)NC(CCO)C4=CC=C(Cl)C=C4
Purity
99.25%
Solubility
DMSO 100 mg/mL
Target synonyms
AZD-5363
Capivasertib (AZD5363)

Capivasertib (AZD5363)

$126.50 USD