Carfilzomib

Vendor: Abmole

Type: Molecular

SKU: M2152

$230.00 USD
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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Bioactivity
Carfilzomib (PR-171) is an irreversible proteasome inhibitor with an IC50 of <5 nM. Carfilzomib irreverently selectively binds to the active site containing n-terminal threonine of the 20S proteasome and proteolytic core particles of the 26S proteasome.*The compound is unstable in solutions, freshly prepared is recommended.
Casnumber
868540-17-4
Formula
C40H57N5O7
Mw
719.91
Psmiles
CC(C)CC(NC(=O)C(CCC1=CC=CC=C1)NC(=O)CN2CCOCC2)C(=O)NC(CC3=CC=CC=C3)C(=O)NC(CC(C)C)C(=O)C4(C)CO4
Purity
>99.0%
Solubility
DMSO 65 mg/mL
Target synonyms
PR-171
Carfilzomib

Carfilzomib

$230.00 USD