Caspase-3 rabbit pAb

Name: Caspase-3 rabbit pAb
Brand: ELK Biotechnology
Price: 148.0 USD
Availability: InStock

Vendor: ELK Biotechnology

SKU: ES1854

$148.00 USD

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Applications

WB;IHC;IF;ELISA

Cellular localization

Cytoplasm.

Clonality

Polyclonal

Concentration

1 mg/ml

Geneid human

836

Human swiss prot no

P42574

Immunogen

The antiserum was produced against synthesized peptide derived from human Caspase 3. AA range:116-165

Isotype

IgG

Observed band

35kD

Product weight

0.005kg

Reactivity

Human;Mouse;Rat;Fish

Recommended dilutions

Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. IF 1:100-300 Not yet tested in other applications.

Source

Rabbit

Storage

-20°C/1 year

Background

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein. [provided by RefSeq, Jul 2008],

Caspase-3 rabbit pAb

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