Caspase-9 (phospho Ser196) rabbit pAb

Name: Caspase-9 (phospho Ser196) rabbit pAb
Brand: ELK Biotechnology
Price: 148.0 USD
Availability: InStock

Vendor: ELK Biotechnology

SKU: ES7740

$148.00 USD

Shipping calculated at checkout.

Documents

Manuals

Supplier image

Available in stock (100)

Customs clearance fees may apply
Worldwide shipping available.

For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Applications

WB;IHC;IF;ELISA

Cellular localization

nucleus,mitochondrion,cytosol,apoptosome,

Clonality

Polyclonal

Concentration

1 mg/ml

Geneid human

842

Human swiss prot no

P55211

Immunogen

The antiserum was produced against synthesized peptide derived from human Caspase 9 around the phosphorylation site of Ser196. AA range:162-211

Isotype

IgG

Observed band

46kD

Product weight

0.005kg

Reactivity

Human;Rat;Mouse;

Recommended dilutions

Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

Source

Rabbit

Storage

-20°C/1 year

Background

CASP9 encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Caspase 9 can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. Caspase 9 is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants.

Caspase-9 (phospho Ser196) rabbit pAb

Documents

Product Overview

Background

Documents

Documents

Product Citations

More Info