Cathepsin G rabbit pAb
Vendor: ELK Biotechnology
SKU: ES4900
Regular price
$148.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB;ELISA
Cellular localization
Cell membrane ; Peripheral membrane protein . Cytoplasmic granule . Secreted . Cytoplasm, cytosol . Lysosome . Nucleus . Secreted by activated neutrophils (PubMed:3390156). Detected in synovial fluid (PubMed:32144329). Localizes to lysosomes in B cells where it is not endogenously synthesized but is internalized from the cell membrane (PubMed:15100291). Localizes to the nucleus during apoptosis (PubMed:11259672). .
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
1511
Human swiss prot no
P08311
Immunogen
The antiserum was produced against synthesized peptide derived from human Cathepsin G. AA range:67-116
Isotype
IgG
Observed band
22kD
Product weight
0.005kg
Reactivity
Human;Rat;Mouse;
Recommended dilutions
Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.
Source
Rabbit
Storage
-20°C/1 year
Background
Background
The protein encoded by this gene, a member of the peptidase S1 protein family, is found in azurophil granules of neutrophilic polymorphonuclear leukocytes. The encoded protease has a specificity similar to that of chymotrypsin C, and may participate in the killing and digestion of engulfed pathogens, and in connective tissue remodeling at sites of inflammation. In addition, the encoded protein is antimicrobial, with bacteriocidal activity against S. aureus and N. gonorrhoeae. Transcript variants utilizing alternative polyadenylation signals exist for this gene. [provided by RefSeq, Sep 2014],
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Product Citations
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More Info
More Info
Cathepsin G rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per

