CD3-ε rabbit pAb

CD3-ε rabbit pAb

Item number: ES7974
Availability: In Stock
$148.00
$148.00
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Size: 50μL
Subtotal: $148.00
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CD3-ε rabbit pAb

CD3-ε rabbit pAb

$148.00

CD3-ε rabbit pAb

$148.00
Size: 50μL
Product weight
0.005kg
Reactivity
Human;Rat;Mouse;;Monkey
Applications
WB;IHC;IF;ELISA
Source
Rabbit
Recommended dilutions
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Immunogen
The antiserum was produced against synthesized peptide derived from human CD3-epsilon. AA range:22-71
Isotype
IgG
Clonality
Polyclonal
Concentration
1 mg/ml
Observed band
21kD
Geneid human
916
Human swiss prot no
P07766
Cellular localization
Cell membrane ; Single-pass type I membrane protein .
The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008],

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