CD4 rabbit pAb

CD4 rabbit pAb

Vendor: ELK Biotechnology

SKU: ES1909

$148.00 USD
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Available in stock (100)

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Applications
WB;IHC;IF;ELISA
Cellular localization
Cell membrane ; Single-pass type I membrane protein . Localizes to lipid rafts (PubMed:12517957, PubMed:9168119). Removed from plasma membrane by HIV-1 Nef protein that increases clathrin-dependent endocytosis of this antigen to target it to lysosomal degradation. Cell surface expression is also down-modulated by HIV-1 Envelope polyprotein gp160 that interacts with, and sequesters CD4 in the endoplasmic reticulum.
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
920
Human swiss prot no
P01730
Immunogen
The antiserum was produced against synthesized peptide derived from human CD4. AA range:401-450
Isotype
IgG
Observed band
51kD
Product weight
0.005kg
Reactivity
Human;Mouse
Recommended dilutions
Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. IF 1:100-300 Not yet tested in other applications.
Source
Rabbit
Storage
-20°C/1 year
CD4 rabbit pAb

CD4 rabbit pAb

$148.00 USD