CENPI rabbit pAb
Vendor: ELK Biotechnology
SKU: ES10522
Regular price
$148.00 USD
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For research use only — not intended for clinical or diagnostic purposes.
Product Overview
Product Overview
Applications
WB;ELISA
Cellular localization
Nucleus. Chromosome, centromere. Localizes exclusively in the centromeres. The CENPA-CAD complex is probably recruited on centromeres by the CENPA-NAC complex.
Clonality
Polyclonal
Concentration
1 mg/ml
Geneid human
2491
Human swiss prot no
Q92674
Immunogen
Synthesized peptide derived from human protein . at AA range: 10-90
Isotype
IgG
Observed band
83kD
Product weight
0.005kg
Reactivity
Human;Rat;Mouse;
Recommended dilutions
WB 1:500-2000 ELISA 1:5000-20000
Source
Rabbit
Storage
-20°C/1 year
Background
Background
This gene encodes a centromere protein that is a component of the CENPA-NAC (nucleosome-associated) complex. This complex is critical for accurate chromosome alignment and segregation and it ensures proper mitotic progression. This protein regulates the recruitment of kinetochore-associated proteins that are required to generate the spindle checkpoint signal. The product of this gene is involved in the response of gonadal tissues to follicle-stimulating hormone. Mutations in this gene may be involved in human X-linked disorders of gonadal development and gametogenesis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 13. [provided by RefSeq, Jan 2016],
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More Info
More Info
CENPI rabbit pAb
Regular price
$148.00 USD
Sale price
Regular price
Unit price
/per
