Cleaved-CD97α (L530) rabbit pAb

Name: Cleaved-CD97α (L530) rabbit pAb
Brand: ELK Biotechnology
Price: 148.0 USD
Availability: InStock

Vendor: ELK Biotechnology

SKU: ES8096

$148.00 USD

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For research use only — not intended for clinical or diagnostic purposes.

Product Overview

Applications

WB;ELISA

Cellular localization

Cell membrane ; Multi-pass membrane protein .; [Adhesion G protein-coupled receptor E5 subunit alpha]: Secreted, extracellular space .

Clonality

Polyclonal

Concentration

1 mg/ml

Geneid human

976

Human swiss prot no

P48960

Immunogen

The antiserum was produced against synthesized peptide derived from human CD97alpha. AA range:481-530

Isotype

IgG

Observed band

55kD

Product weight

0.005kg

Reactivity

Human;Rat;Mouse;

Recommended dilutions

Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.

Source

Rabbit

Storage

-20°C/1 year

Background

This gene encodes a member of the EGF-TM7 subfamily of adhesion G protein-coupled receptors, which mediate cell-cell interactions. These proteins are cleaved by self-catalytic proteolysis into a large extracellular subunit and seven-span transmembrane subunit, which associate at the cell surface as a receptor complex. The encoded protein may play a role in cell adhesion as well as leukocyte recruitment, activation and migration, and contains multiple extracellular EGF-like repeats which mediate binding to chondroitin sulfate and the cell surface complement regulatory protein CD55. Expression of this gene may play a role in the progression of several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms with 3 to 5 EGF-like repeats have been observed for this gene. This gene is found in a cluster with other EGF-TM7 genes on the short arm of chromosome 1

Cleaved-CD97α (L530) rabbit pAb

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